Description
PrymaLab · Research use only
Preloaded Autoinjector | BPC-157 | 3ml Pen | 5mg/ml
BPC-157 pen: 15 mg of the 15-residue peptide in 3 mL of solution at 5 mg/mL
BPC-157 is a synthetic 15-residue peptide based on a sequence from human gastric juice. This BPC-157 pen is a preloaded autoinjector holding a 3 mL cartridge of ready-made solution at 5 mg/mL, 15 mg of peptide in all, so there is no powder to dissolve. Studies of BPC-157 concern tendon, gut and skin injury and the growth of new blood vessels, and nearly all of them were carried out in rats or cultured cells.
Specifications
| Property | Value |
|---|---|
| Compound | BPC-157 Body Protection Compound-157; pentadecapeptide |
| CAS number | 137525-51-0 |
| Molecular formula | C62H98N16O22 |
| Theoretical mass | 1419.6 Da |
| Sequence / structure | H-GEPPPGKPADDAGLV-OH (15 residues; free N- and C-termini) |
| Contents | BPC-157: 15 mg per 3 mL pen (0.5% w/v) |
| Form | Sterile aqueous solution in bacteriostatic water (0.9% benzyl alcohol), supplied in a 3 mL glass cartridge inside a preloaded autoinjector pen fitted with a needle |
| Storage, sealed | Store at 2–8 °C in the original carton, protected from light |
| Safety data sheet | PL-SDS-020 |
What is in the pen
The cartridge holds 3 mL of sterile aqueous solution. The peptide is the same BPC-157 sold in the freeze-dried vials, at 0.5% w/v: 5 mg/mL, 15 mg per pen, or roughly 10.6 µmol at the theoretical mass of 1419.6 Da. It is dissolved in bacteriostatic water containing 0.9% benzyl alcohol as an antimicrobial preservative. The safety data sheet does not classify BPC-157 as hazardous; benzyl alcohol carries statements for harm if swallowed or inhaled, serious eye irritation and possible allergic skin reactions.
Keep the pen at 2 to 8 °C in its carton, out of the light, and never let it freeze. Discard a pen that has frozen or whose solution looks discoloured or cloudy, and keep the cap on whenever it is not being handled. For peptide that stays dry until needed, the BPC-157 5 mg vial holds the same sequence, and peptide pen vs vial sets out the general trade-offs.
What the research covers
The mechanism proposed most often for BPC-157 runs through the growth of new blood vessels. Hsieh and colleagues found that it increased vessel density in the chick chorioallantoic membrane and in endothelial tube-formation assays, and that blood flow returned faster to ischaemic hind-limb muscle in rats1. In human endothelial cells it raised VEGFR2 levels without changing VEGF-A, drove the receptor’s internalisation and switched on VEGFR2-Akt-eNOS signalling, and dynasore, an inhibitor of endocytosis, suppressed both the signalling and the extra tube formation1.
Work from another group pointed the same way. Huang and colleagues applied BPC-157 to alkali burns on rat skin and reported faster wound closure, better granulation tissue, re-epithelialisation and collagen deposition, and more VEGF in the wounded tissue; in human umbilical vein endothelial cells the peptide promoted proliferation, migration and tube formation2.
These are rodent and cell results. A 2019 review of the musculoskeletal literature pointed out that most studies used small rodents, that efficacy in humans had not been confirmed, and that only a handful of groups had examined the peptide closely3. No study cited here used a solution in a pen or measured how long BPC-157 stays intact in bacteriostatic water. The BPC-157 research guide covers the gut, tendon and muscle work in full.
How each lot is tested
Every lot is tested in PrymaLab’s own laboratory in Ashland, Kentucky before release: RP-HPLC for purity, LC-MS for identity, Karl Fischer titration for water, LAL for endotoxin and USP <71> for sterility. Published certificates are listed on the results page and can be checked by number and key on the verify page. The certificate covers the peptide lot used to fill the pen, not the finished solution. These are in-house results from PrymaLab Analytical, not an independent test, and the lab is not accredited to ISO 17025. The third-party testing guarantee on this page still applies: if any independent laboratory finds the wrong compound, or less than the stated purity or amount, the order is refunded and the cost of the test is reimbursed.
Frequently asked questions
How is the BPC-157 pen different from the BPC-157 vials?
The vials hold freeze-dried peptide that is kept at −20 °C and dissolved in the lab when needed, at whatever concentration the work calls for. The pen holds the same peptide already in bacteriostatic water at a fixed 5 mg/mL and is kept at 2 to 8 °C.
Which certificate applies to the pen?
The certificate is for the BPC-157 lot used to fill the pen, not for the finished solution in the cartridge. Published certificates are listed on the testing results page and can be confirmed by number and key on the verify page.
How long does the solution in the pen stay stable?
None of the studies cited on this page measured BPC-157 stability in bacteriostatic water, so there is no published figure to give. Follow the safety data sheet: refrigerate, protect from light, never freeze, and discard the pen if the solution turns cloudy or changes colour.
Can the pen be used in people or animals?
No. Like every PrymaLab product it is a laboratory research material. It has not been approved by the FDA or any comparable authority for human or veterinary use, and it must not be given to people or animals.
References
- Hsieh MJ, Liu HT, Wang CN, et al. Therapeutic potential of pro-angiogenic BPC157 is associated with VEGFR2 activation and up-regulation. J Mol Med (Berl). 2017;95(3):323-333. DOI · PubMed
- Huang T, Zhang K, Sun L, et al. Body protective compound-157 enhances alkali-burn wound healing in vivo and promotes proliferation, migration, and angiogenesis in vitro. Drug Des Devel Ther. 2015;9:2485-99. DOI · PubMed
- Gwyer D, Wragg NM, Wilson SL. Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing. Cell Tissue Res. 2019;377(2):153-159. DOI · PubMed
Research use only
For laboratory research use only. This product is not a drug, food, cosmetic or dietary supplement, is not approved by the FDA or any comparable authority for human or veterinary use, and must not be given to people or animals. It is sold to qualified researchers and institutions, and the buyer is responsible for lawful handling and disposal.
Other formats of BPC-157
BPC-157 is also stocked as BPC-157 10MG, BPC-157 Capsules (60/500mcg), BPC-157 Peptide Nasal Spray, BPC-157 + TB500 (10mg/10mg) "Wolverine Blend", BPC 157 5mg + TB500 5mg, TB-500 (Thymosin Beta-4) 5mg and TB-500 (Thymosin Beta-4) 10mg. Each listing states its own quantity and concentration, and the pen and vial comparison explains what changes between formats.
7 reviews for Preloaded Autoinjector | BPC-157 | 3ml Pen | 5mg/ml