Description
PrymaLab · Research use only
Semaglutide 30mg
The largest semaglutide fill: 30 mg of freeze-dried GLP-1 analogue
Semaglutide 30 mg is the largest of PrymaLab’s five semaglutide fills, with 30 mg of the peptide as freeze-dried powder in one vial. Semaglutide is a 31-residue GLP-1 receptor agonist that carries a C18 diacid for albumin binding. The research on it covers that design, receptor pharmacology and clinical trials, among them a phase 3 trial in which it was the comparator for tirzepatide.
Specifications
| Property | Value |
|---|---|
| Compound | Semaglutide NN9535; GLP-1 receptor agonist |
| CAS number | 910463-68-2 |
| Molecular formula | C187H291N45O59 |
| Theoretical mass | 4113.6 Da |
| Sequence / structure | H-H-Aib-EGTFTSDVSSYLEGQAAK(2×OEG-γGlu-C18 diacid)EFIAWLVRGRG-OH (31 residues; Aib8 and Arg34 in GLP-1 numbering; Lys26 acylated with octadecanedioic acid via two OEG spacers and γ-Glu; free C-terminus) |
| Label claim | 30 mg/vial |
| Form | Lyophilized (freeze-dried) powder or cake in a sealed glass vial with a rubber stopper and aluminium crimp cap |
| Storage, sealed | −20 °C, desiccated, dark |
| Purity specification | 99.0% or higher by RP-HPLC |
| Lot certificate | Results for the lot now shipping are in the certificate panel on this page |
| Safety data sheet | PL-SDS-146 |
Other fills
This is the 30 mg fill. The Semaglutide 5mg page is the main listing for this compound, with the full research summary and every fill side by side. Other fills: 5 mg, 10 mg, 15 mg, 20 mg.
What the research covers
A fill this size raises a stability question that the cited literature answers only in general terms. Reviews of protein stability separate chemical from physical degradation and compare stabilisation in solution with the dried state1; none of the papers here measured semaglutide’s life in a reconstituted research vial. In clinical work semaglutide was the active comparator in SURPASS-2, a 40-week phase 3 trial in adults with type 2 diabetes2. The Semaglutide 5 mg page has the full summary.
The Semaglutide Benefits guide covers the literature in more depth.
How each lot is tested
Every lot is tested in PrymaLab’s own laboratory in Ashland, Kentucky before release: RP-HPLC for purity, LC-MS for identity, Karl Fischer titration for water, LAL for endotoxin and USP <71> for sterility. The results for the lot now shipping are in the certificate panel on this page, and the certificate number, key and QR code can be checked on the verify page. These are in-house results from PrymaLab Analytical, not an independent test, and the lab is not accredited to ISO 17025. The third-party testing guarantee on this page still applies: if any independent laboratory finds the wrong compound, or less than the stated purity or amount, the order is refunded and the cost of the test is reimbursed.
Frequently asked questions
What limits how much of a 30 mg vial can be used at once?
Stability in solution rather than the powder. Sealed and dry, the vial keeps at −20 °C. Once dissolved it belongs at 2 to 8 °C away from light, for a period your laboratory has established, so plan the volume around how quickly the solution will be used.
How many micromoles are in 30 mg of semaglutide?
About 7.3 µmol, calculated from the theoretical mass of 4113.6 Da. The certificate's water figure means the peptide content runs a little under that, which matters most when exact molar amounts are needed.
References
- Manning MC, Chou DK, Murphy BM, et al. Stability of protein pharmaceuticals: an update. Pharm Res. 2010;27(4):544-75. DOI · PubMed
- Frías JP, Davies MJ, Rosenstock J, et al. Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes. N Engl J Med. 2021;385(6):503-515. DOI · PubMed
Research use only
For laboratory research use only. Semaglutide 30mg is not a drug, food, cosmetic or dietary supplement, is not approved by the FDA or any comparable authority for human or veterinary use, and must not be given to people or animals. It is sold to qualified researchers and institutions, and the buyer is responsible for lawful handling and disposal.
Other formats of Semaglutide
Semaglutide is also stocked as cagrilintide 2.5mg + semaglutide 2.5mg, Cagrilintide 5mg + Semaglutide 5mg, Cagrilintide 20mg preloaded 3ml pen and Cagrilintide 5mg. Each listing states its own quantity and concentration, and the pen and vial comparison explains what changes between formats.
Reviews
There are no reviews yet.