Description
PrymaLab · Research use only
Sermorelin 5mg
Sermorelin, GHRH(1-29) amide, in the smaller 5 mg freeze-dried fill
Sermorelin reproduces the N-terminal 29 residues of growth hormone-releasing hormone and ends in an amide. This vial holds 5 mg of it as freeze-dried powder, half the amount in the 10 mg main fill, and it is made and tested as a separate lot. Studies of sermorelin deal with growth hormone release from the pituitary, clinical work in children and the chemistry of the peptide in water.
Specifications
| Property | Value |
|---|---|
| Compound | Sermorelin GHRH(1–29)-NH₂; GRF(1–29) |
| CAS number | 86168-78-7 |
| Molecular formula | C149H246N44O42S |
| Theoretical mass | 3357.9 Da |
| Sequence / structure | H-YADAIFTNSYRKVLGQLSARKLLQDIMSR-NH₂ (29 residues; C-terminal amide) |
| Label claim | 5 mg/vial |
| Form | Lyophilized (freeze-dried) powder or cake in a sealed glass vial with a rubber stopper and aluminium crimp cap |
| Storage, sealed | −20 °C, desiccated, dark |
| Purity specification | 99.0% or higher by RP-HPLC |
| Lot certificate | Results for the lot now shipping are in the certificate panel on this page |
| Safety data sheet | PL-SDS-150 |
Other fills
This is the 5 mg fill. The Sermorelin 10mg page is the main listing for this compound, with the full research summary and every fill side by side. Other fills: 10 mg.
What the research covers
Sermorelin is the shortest synthetic peptide reported to retain the full biological activity of GHRH, and it acts specifically on growth hormone secretion by the anterior pituitary1. Dissolved, it degrades mainly at Asp3 and Asn8, and it was most stable between pH 4 and 5 in the work that mapped those reactions2. The Sermorelin 10 mg page carries the full research summary, from the clinical studies in children to the short trial in older men.
The Sermorelin Benefits guide covers the literature in more depth.
How each lot is tested
Every lot is tested in PrymaLab’s own laboratory in Ashland, Kentucky before release: RP-HPLC for purity, LC-MS for identity, Karl Fischer titration for water, LAL for endotoxin and USP <71> for sterility. The results for the lot now shipping are in the certificate panel on this page, and the certificate number, key and QR code can be checked on the verify page. These are in-house results from PrymaLab Analytical, not an independent test, and the lab is not accredited to ISO 17025. The third-party testing guarantee on this page still applies: if any independent laboratory finds the wrong compound, or less than the stated purity or amount, the order is refunded and the cost of the test is reimbursed.
Frequently asked questions
Is the 5 mg vial the same peptide as the 10 mg vial?
Yes. It is the same 29-residue sequence with a C-terminal amide and a theoretical mass of 3357.9 Da. 5 mg works out to about 1.5 µmol, a little less once the water reported on the certificate is allowed for. It has its own lot number and certificate.
Does a smaller fill matter for a peptide that breaks down in solution?
It can. Sermorelin deamidates and isomerises in water, so a smaller fill means less solution standing at 2 to 8 °C before it is used up. The sealed powder is kept at −20 °C, dry and dark, until you reconstitute it.
Is this vial for human use?
No. It is sold for laboratory research only, is not approved for human or veterinary use, and must not be given to people or animals.
References
- Prakash A, Goa KL. Sermorelin: a review of its use in the diagnosis and treatment of children with idiopathic growth hormone deficiency. BioDrugs. 1999;12(2):139-57. DOI · PubMed
- Bongers J, Heimer EP, Lambros T, et al. Degradation of aspartic acid and asparagine residues in human growth hormone-releasing factor. Int J Pept Protein Res. 1992;39(4):364-74. DOI · PubMed
Research use only
For laboratory research use only. Sermorelin 5mg is not a drug, food, cosmetic or dietary supplement, is not approved by the FDA or any comparable authority for human or veterinary use, and must not be given to people or animals. It is sold to qualified researchers and institutions, and the buyer is responsible for lawful handling and disposal.
Other formats of Sermorelin
Sermorelin is also stocked as Sermorelin 6mg preloaded 3ml pen. Each listing states its own quantity and concentration, and the pen and vial comparison explains what changes between formats.
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