Description
PrymaLab · Research use only
Preloaded Autoinjector | Selank | 3ml Pen | 1mg/ml
Selank in bacteriostatic water at 1 mg/mL, 3 mg in a preloaded 3 mL pen
Selank is the seven-residue peptide Thr-Lys-Pro-Arg-Pro-Gly-Pro, tuftsin with a Pro-Gly-Pro tail attached. In this listing it is already in solution: a preloaded autoinjector pen with a 3 mL cartridge at 1 mg/mL, 3 mg of peptide per pen. Research on Selank, largely Russian, has measured gene expression in the rat brain and set Selank beside related tuftsin peptides in rodent behaviour studies.
Specifications
| Property | Value |
|---|---|
| Compound | Selank Tuftsin-Pro-Gly-Pro heptapeptide (TKPRPGP) |
| CAS number | 129954-34-3 |
| Molecular formula | C33H57N11O9 |
| Theoretical mass | 751.9 Da |
| Sequence / structure | H-TKPRPGP-OH (7 residues; free N- and C-termini) |
| Contents | Selank: 3 mg per 3 mL pen (0.1% w/v) |
| Form | Sterile aqueous solution in bacteriostatic water (0.9% benzyl alcohol), supplied in a 3 mL glass cartridge inside a preloaded autoinjector pen fitted with a needle |
| Storage, sealed | Store at 2–8 °C in the original carton, protected from light |
| Safety data sheet | PL-SDS-144 |
What is in the pen
Each pen carries a 3 mL glass cartridge of sterile aqueous solution. Selank makes up 0.1% w/v, which works out to 1 mg/mL and 3 mg per pen, dissolved in bacteriostatic water containing 0.9% benzyl alcohol as an antimicrobial preservative. The safety data sheet does not classify the peptide. It lists benzyl alcohol as harmful if swallowed or inhaled, a serious eye irritant and a possible cause of allergic skin reactions.
Store the pen at 2 to 8 °C in its original carton, protected from light, and keep it capped once it is in use. Never freeze it. A pen whose solution has frozen, changed colour or become cloudy should be discarded. The same peptide is sold dry as the Selank 5 mg vial, and the general trade-offs are covered in peptide pen vs vial.
What the research covers
Selank’s first four residues are tuftsin, a peptide that later research treated as an immunomodulator; a 2017 review of 86 papers sorted tuftsin analogues by anti-tumour, anti-inflammatory, antimicrobial and antiviral activity1. The Selank work itself has moved toward the brain. In rats, Selank changed the expression of 45 of 84 neurotransmission genes in the frontal cortex at one hour and 22 at three hours, and those changes tracked the ones GABA produced, which led the authors to propose allosteric modulation of the GABAergic system2.
A solution raises a different question, about where the peptide ends up in the container. In a study of eight radiolabelled peptides held for 48 hours in glass and plastic tubes, recovery depended on the material and its coating, fell with siliconising and rose with added albumin3. Selank was not part of that study, and no measurement of Selank in a glass cartridge, or of its stability in bacteriostatic water, is among the references here. For the pen, the storage terms on the safety data sheet are the ones that apply.
The Selank literature is mostly Russian and comes from a handful of groups. The Semax vs Selank guide covers the compound in more depth, including its tuftsin lineage.
The Selank Peptide guide covers the literature in more depth.
How each lot is tested
Every lot is tested in PrymaLab’s own laboratory in Ashland, Kentucky before release: RP-HPLC for purity, LC-MS for identity, Karl Fischer titration for water, LAL for endotoxin and USP <71> for sterility. Published certificates are listed on the results page and can be checked by number and key on the verify page. The certificate covers the peptide lot used to fill the pen, not the finished solution. These are in-house results from PrymaLab Analytical, not an independent test, and the lab is not accredited to ISO 17025. The third-party testing guarantee on this page still applies: if any independent laboratory finds the wrong compound, or less than the stated purity or amount, the order is refunded and the cost of the test is reimbursed.
Frequently asked questions
How does the pen differ from the Selank vials?
The vials contain freeze-dried Selank kept at −20 °C and dissolved by the laboratory when it is needed. The pen contains 3 mg already in bacteriostatic water at 1 mg/mL, stored at 2 to 8 °C, so its concentration is fixed from the start.
What does the certificate cover for the pen?
The certificate applies to the Selank peptide lot used to fill the pen, not to the finished solution in the cartridge. The testing section on this page explains what the certificates report and how to check one by number and key.
Why does the pen need refrigeration if Selank has no methionine?
Lacking methionine removes one oxidation route, not every way a solution can change. The safety data sheet sets 2 to 8 °C, protected from light and never frozen, and says to discard a pen whose solution has frozen, discoloured or turned cloudy.
Can the pen be used in people or animals?
No. The pen is sold only for laboratory research, is not approved by the FDA for human or veterinary use, and must not be given to people or animals. This page describes its contents and storage, nothing more.
References
- Siebert A, Gensicka-Kowalewska M, Cholewinski G, et al. Tuftsin – Properties and Analogs. Curr Med Chem. 2017;24(34):3711-3727. DOI · PubMed
- Volkova A, Shadrina M, Kolomin T, et al. Selank Administration Affects the Expression of Some Genes Involved in GABAergic Neurotransmission. Front Pharmacol. 2016;7:31. DOI · PubMed
- Goebel-Stengel M, Stengel A, Taché Y, et al. The importance of using the optimal plasticware and glassware in studies involving peptides. Anal Biochem. 2011;414(1):38-46. DOI · PubMed
Research use only
For laboratory research use only. This product is not a drug, food, cosmetic or dietary supplement, is not approved by the FDA or any comparable authority for human or veterinary use, and must not be given to people or animals. It is sold to qualified researchers and institutions, and the buyer is responsible for lawful handling and disposal.
Other formats of Selank
Selank is also stocked as Selank 10mg Nasal Spray and Selank 11mg. Each listing states its own quantity and concentration, and the pen and vial comparison explains what changes between formats.
1 review for Preloaded Autoinjector | Selank | 3ml Pen | 1mg/ml