Description
PrymaLab · Research use only
Preloaded Autoinjector | GLOW BLEND | 3ml Pen | 50mg/ml
GHK-Cu, BPC-157 and TB-500 dissolved at 50 mg/mL in a preloaded 3 mL pen
The GLOW pen carries the three peptides of the GLOW blend, GHK-Cu, BPC-157 and full-length thymosin beta-4 (TB-500), as a ready-made solution: 3 mL at 50 mg/mL total, 150 mg in the pen. Its proportions follow the 70 mg vial. Research on GLOW is research on its parts: the copper complex in fibroblast cultures, BPC-157 in rat and endothelial cell studies, and thymosin beta-4 in actin biology.
Specifications
| Property | Value |
|---|---|
| Components | GHK-Cu (Copper tripeptide-1; Gly-His-Lys · Cu(II)) BPC-157 (Body Protection Compound-157; pentadecapeptide) TB-500 (Thymosin β4); N-acetyl thymosin β4, full-length 43-residue peptide |
| GHK-Cu CAS number | 89030-95-5 |
| BPC-157 CAS number | 137525-51-0 |
| TB-500 (Thymosin β4) CAS number | 77591-33-4 |
| Contents | GHK-Cu: 107 mg per 3 mL pen (3.6% w/v) BPC-157: 21.4 mg per 3 mL pen (0.71% w/v) TB-500 (Thymosin β4): 21.4 mg per 3 mL pen (0.71% w/v) |
| Form | Sterile aqueous solution in bacteriostatic water (0.9% benzyl alcohol), supplied in a 3 mL glass cartridge inside a preloaded autoinjector pen fitted with a needle |
| Storage, sealed | Store at 2–8 °C in the original carton, protected from light |
| Safety data sheet | PL-SDS-070 |
What is in the pen
The safety data sheet for this pen (PL-SDS-070) lists GHK-Cu at 107 mg (3.6% w/v), BPC-157 at 21.4 mg (0.71% w/v) and TB-500 at 21.4 mg (0.71% w/v) per 3 mL pen. That is 150 mg in all and the 5:1:1 mass ratio of the GLOW 70 mg vial, not the 7:1:2 ratio of GLOW 50 mg. The peptides are dissolved in bacteriostatic water with 0.9% benzyl alcohol, which the sheet classifies as harmful if swallowed or inhaled, an eye irritant and a skin sensitiser; the three peptides are not classified. The copper complex makes the solution clear blue to blue-violet.
Store the pen at 2 to 8 °C in its original carton, protected from light, and keep it capped once in use. Never freeze it. A pen whose solution has frozen, discoloured or clouded should be thrown away.
What the research covers
None of the published work on these peptides used them together. GHK-Cu, the largest component, is a plasma tripeptide whose copper complex has been reported to increase collagen, elastin and glycosaminoglycan synthesis and to support repair in skin, bone, liver and other tissues, according to a 2018 review by Pickart and Margolina1. BPC-157 has been tied to blood vessel growth: it raised VEGFR2 expression and switched on VEGFR2-Akt-eNOS signalling in human endothelial cells, and blood flow returned sooner in rat ischemic muscle2. The same study found more vessels forming in chick embryo membranes and in endothelial tube assays2. Thymosin beta-4 is the main peptide that sequesters G-actin inside cells, where each molecule holds a single actin monomer back from filaments until the cell draws on that reserve3. Outside cells it has been found in plasma and wound fluid, though the mechanisms of its extracellular effects were unknown when Huff’s group reviewed them3.
The evidence for each is preclinical, and none of it concerns a solution of the three held in bacteriostatic water. How the peptides behave together over the life of a pen, including any effect of the copper complex on the other two, has not been studied. The GLOW peptide guide covers the component literature in full.
How each lot is tested
Every lot is tested in PrymaLab’s own laboratory in Ashland, Kentucky before release: RP-HPLC for purity, LC-MS for identity, Karl Fischer titration for water, LAL for endotoxin and USP <71> for sterility. Published certificates are listed on the results page and can be checked by number and key on the verify page. The certificate covers the peptide lot used to fill the pen, not the finished solution. These are in-house results from PrymaLab Analytical, not an independent test, and the lab is not accredited to ISO 17025. The third-party testing guarantee on this page still applies: if any independent laboratory finds the wrong compound, or less than the stated purity or amount, the order is refunded and the cost of the test is reimbursed.
Frequently asked questions
Does the pen use the GLOW 70 mg or GLOW 50 mg ratio?
The 70 mg ratio. The safety data sheet gives 107 mg GHK-Cu and 21.4 mg each of BPC-157 and TB-500 per pen, which is 5:1:1 by mass. The GLOW 50 mg vial uses a different 7:1:2 ratio and has no pen equivalent.
What does the certificate cover?
The certificate covers the peptide lot used to fill the pen, tested in PrymaLab's own laboratory, rather than the finished solution in the cartridge. The testing section below describes the tests and how to check a certificate on the verify page.
How long is the solution stable?
No published study has measured the stability of these three peptides together in solution. Follow the safety data sheet: keep the pen at 2 to 8 °C, away from light and unfrozen, and discard it if the solution freezes, changes colour or turns cloudy.
Is the GLOW pen for human use?
No. It is sold only for laboratory research, carries no FDA or other approval for human or veterinary use, and must not be used on people or animals.
References
- Pickart L, Margolina A. Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. Int J Mol Sci. 2018;19(7). DOI · PubMed
- Hsieh MJ, Liu HT, Wang CN, et al. Therapeutic potential of pro-angiogenic BPC157 is associated with VEGFR2 activation and up-regulation. J Mol Med (Berl). 2017;95(3):323-333. DOI · PubMed
- Huff T, Müller CS, Otto AM, et al. beta-Thymosins, small acidic peptides with multiple functions. Int J Biochem Cell Biol. 2001;33(3):205-20. DOI · PubMed
Research use only
For laboratory research use only. This product is not a drug, food, cosmetic or dietary supplement, is not approved by the FDA or any comparable authority for human or veterinary use, and must not be given to people or animals. It is sold to qualified researchers and institutions, and the buyer is responsible for lawful handling and disposal.
Other formats of GLOW BLEND
GLOW BLEND is also stocked as GLOW BLEND 50MG. Each listing states its own quantity and concentration, and the pen and vial comparison explains what changes between formats.
9 reviews for Preloaded Autoinjector | GLOW BLEND | 3ml Pen | 50mg/ml