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VIP5 5MG (Vasoactive Intestinal Peptide)

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Safety data sheet PL-SDS-184 GHS: not classified as hazardous · Read the SDS · PDF

VIP5 5 mg: vasoactive intestinal peptide (1-28) amide, freeze-dried in a sealed vial and produced as its own lot. Each lot is tested in PrymaLab’s own laboratory and has a certificate. For laboratory research use only.

Description

PrymaLab · Research use only

VIP5 5MG (Vasoactive Intestinal Peptide)

Vasoactive intestinal peptide in the 5 mg freeze-dried fill

VIP5 is PrymaLab’s name for vasoactive intestinal peptide, a 28-residue neuropeptide that acts on the VPAC1 and VPAC2 receptors. This vial is the 5 mg fill of freeze-dried powder, made and tested as its own lot; the 10 mg vial is the main listing. Studies of VIP concern its receptor pharmacology and its roles in nerve, gut and immune function.

Specifications

VIP5 5MG (Vasoactive Intestinal Peptide) at a glance
Property Value
Compound Vasoactive intestinal peptide (1-28) amide; aviptadil
CAS number 40077-57-4
Molecular formula C147H238N44O42S
Label claim 5 mg per vial
Form Lyophilized (freeze-dried) powder or cake in a sealed glass vial with a rubber stopper and aluminium crimp cap
Safety data sheet PL-SDS-184

Other fills

This is the 5 mg fill. The VIP5 10MG (Vasoactive Intestinal Peptide) page is the main listing for this compound, with the full research summary and every fill side by side. Other fills: 10 mg.

What the research covers

VIP was first isolated from hog intestine as a 28-residue peptide that dilated blood vessels and stimulated breathing1. Its receptors VPAC1 and VPAC2 also bind PACAP with high affinity, so the two peptides overlap in what they can activate, and only PAC1 tells them apart2. The VIP5 10 mg vial page has the full research summary.

The VIP Peptide guide covers the literature in more depth.

How each lot is tested

Every lot is tested in PrymaLab’s own laboratory in Ashland, Kentucky before release: RP-HPLC for purity, LC-MS for identity, Karl Fischer titration for water, LAL for endotoxin and USP <71> for sterility. Published certificates are listed on the results page and can be checked by number and key on the verify page. These are in-house results from PrymaLab Analytical, not an independent test, and the lab is not accredited to ISO 17025. The third-party testing guarantee on this page still applies: if any independent laboratory finds the wrong compound, or less than the stated purity or amount, the order is refunded and the cost of the test is reimbursed.

Frequently asked questions

Is the 5 mg vial the same peptide as the 10 mg?

Yes. Both hold VIP (1-28) amide, CAS 40077-57-4, as freeze-dried powder, and one safety data sheet covers both. The 5 mg fill is a separate lot with its own number and certificate.

When does a 5 mg fill make sense?

When a study uses less peptide per reconstituted vial. A smaller fill leaves less solution waiting at 2 to 8 °C after reconstitution, while the sealed vial is stored the same way as the 10 mg: −20 °C, dry and dark.

References

  1. Said SI, Mutt V. Polypeptide with broad biological activity: isolation from small intestine. Science. 1970;169(3951):1217-8. DOI · PubMed
  2. Harmar AJ, Fahrenkrug J, Gozes I, et al. Pharmacology and functions of receptors for vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide: IUPHAR review 1. Br J Pharmacol. 2012;166(1):4-17. DOI · PubMed

Research use only

For laboratory research use only. VIP5 5MG (Vasoactive Intestinal Peptide) is not a drug, food, cosmetic or dietary supplement, is not approved by the FDA or any comparable authority for human or veterinary use, and must not be given to people or animals. It is sold to qualified researchers and institutions, and the buyer is responsible for lawful handling and disposal.

Other formats of VIP5

VIP5 is also stocked as VIP5 (Vasoactive Intestinal Peptide) 5mg/ml preloaded 3ml pen and VIP 10mg Nasal Spray. Each listing states its own quantity and concentration, and the pen and vial comparison explains what changes between formats.

Additional information

Weight N/A
Dimensions N/A

Safety data sheet PL-SDS-184 · VIP

GHS safety data sheet for this product (lyophilized powder, vial), revision 1.0 of October 3, 2026. Read all 16 sections or download the PDF to keep with the material.

Not classified as hazardous Not classified under OSHA HCS 2012 / GHS. No pictogram, signal word or hazard statement is required; handle as a pharmacologically active laboratory chemical.
CompositionVIP (CAS 40077-57-4) · ≥ 95% (dry basis, as supplied), 5 mg, 10 mg per vial
ClassificationNot classified as hazardous under OSHA HCS 2012 (29 CFR 1910.1200) or UN GHS, on the basis of the supplier safety data sheets consulted.
Physical stateSolid. White to off-white lyophilized powder.
Storage−20 °C (sealed vial), desiccated and protected from light; 2–8 °C acceptable for short periods
HandlingOpen vials only in a clean area. Avoid generating or inhaling dust; weigh or reconstitute inside a ventilated enclosure when the full contents are handled as a dry powder. Reconstitute by adding diluent slowly to the vial wall; do not shake. Wash hands after handling.
First aidEyes: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do; continue rinsing. If eye irritation persists, get medical advice. Skin: Take off contaminated clothing. Wash the skin with plenty of soap and water. If irritation or a rash develops, get medical advice. Ingestion: Rinse mouth. Do not induce vomiting. Call a POISON CENTER or doctor if you feel unwell.
DisposalChemical waste through a licensed contractor; do not pour down the drain.
TransportNot regulated as a dangerous good (DOT / IATA / IMDG).

For laboratory research use only. Not for human or veterinary use.

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