SECTION 1: INTRODUCTION
CJC-1295 DAC 5 MG – Lab Research Supply is a long-acting growth hormone–releasing hormone (GHRH) analog, commonly abbreviated as CJC-1295 with DAC (Drug Affinity Complex). As a laboratory grade growth hormone secretagogue and synthetic peptide analog, it is valued in scientific research for its albumin-binding design that extends systemic exposure, enabling precise studies of endocrine kinetics, receptor pharmacology, and peptide stability.
SECTION 2: RESEARCH APPLICATIONS
- Investigated in studies examining modulation of the growth hormone/IGF-1 axis and pulsatile secretion dynamics.
- Research has explored its role in albumin-binding strategies to enhance half-life and reduce dosing frequency in peptide research.
- In-vitro studies have demonstrated GHRH receptor engagement and downstream cAMP/PKA signaling relevant to endocrine pathway mapping.
- Animal model research suggests effects on biomarkers associated with metabolic regulation, recovery pathways, and tissue remodeling mechanisms.
- Laboratory investigations focus on neuroendocrine cross-talk, including stress and sleep-related regulation of growth hormone release.
- Studies have assessed peptide stability, proteolytic resistance, and structure–activity relationships for optimized pharmacokinetics.
SECTION 3: TECHNICAL SPECIFICATIONS
High purity peptide (≥98% by HPLC), supplied as a lyophilized powder for research use. Appearance: white to off-white solid. Molecular features: GHRH(1-29) amide analog incorporating stabilizing substitutions and a DAC (maleimidopropionyl) moiety designed to form a stable bond with serum albumin, extending residence time. Molecular formula and exact molecular weight are lot-specific due to DAC conjugation; values are confirmed by LC-MS on the Certificate of Analysis. CAS: not uniquely assigned for DAC-conjugated analogs; refer to COA for reference identifiers.
SECTION 4: QUALITY ASSURANCE
Produced under stringent quality controls consistent with GMP-compliant processes for research chemicals. Each batch undergoes third-party HPLC purity assessment and mass spectrometric identity confirmation. Lot-specific Certificates of Analysis are available, including purity, identity, and appearance. Batch traceability and retention samples are maintained to support reproducibility in scientific research.
SECTION 5: STORAGE & HANDLING
Store unopened vials at −20°C or below, protected from light and moisture. When reconstituted (e.g., in sterile water or suitable buffer), aliquot to avoid repeated freeze–thaw cycles; short-term stability at 2–8°C is limited, with longer-term storage recommended at −20°C. Follow aseptic technique for in-vitro studies. This research peptide is hygroscopic; allow vial to reach room temperature before opening. Shelf life is lot-dependent; consult the COA for stability guidance.
SECTION 6: COMPLIANCE & DISCLAIMERS
This product is intended exclusively for laboratory research use by qualified professionals. Not approved for human consumption, veterinary applications, or clinical use. Purchasers must be affiliated with a research institution or possess appropriate qualifications. All research must comply with applicable local, state, and federal regulations. The statements regarding research applications have not been evaluated by the FDA. Not a drug, food, cosmetic, or household item. Handle as a potent research chemical with appropriate PPE.