SECTION 1: INTRODUCTION

CJC-1295 (NO DAC) 5 MG – Lab Research Supply, also known as Modified GRF(1-29), is a synthetic peptide analog of growth hormone–releasing hormone (GHRH). Classified as a growth hormone secretagogue and research peptide, this laboratory grade material is widely used to interrogate somatotropic signaling in controlled experimental settings. The NO DAC format (no Drug Affinity Complex) preserves short, pulsatile kinetics, making it valuable for time-resolved peptide research across metabolic, neurobiological, and inflammatory models.

SECTION 2: RESEARCH APPLICATIONS

• Investigated in studies examining pulsatile growth hormone axis regulation and downstream IGF-1 pathway signaling in preclinical systems.
• Research has explored its role in metabolic profiling, including energy balance and body composition markers in animal models.
• In-vitro studies have demonstrated receptor engagement consistent with GHRH receptor activation and cAMP-mediated signaling.
• Animal model research suggests potential utility in probing neuroprotective mechanisms and synaptic plasticity under experimental stressors.
• Laboratory investigations focus on anti-inflammatory signaling cascades and recovery responses in tissue repair paradigms.
• Additional peptide research evaluates combinatorial designs with other growth hormone secretagogues to map synergistic signaling dynamics.

SECTION 3: TECHNICAL SPECIFICATIONS

This high purity peptide (≥98% by HPLC) is supplied as a lyophilized, white to off-white powder in a 5 mg fill. Molecular weight (monoisotopic, free base): ~3357.9 Da. Molecular formula: 29–amino acid GHRH analog (tetrasubstituted); exact formula may vary by counterion/salt form. Sequence information: tetrasubstituted GRF(1-29) analog (D-Ala2, Gln8, Ala15, Leu27), commonly referred to as Mod GRF(1-29). CAS: not assigned/varies for this research analog. Appearance: lyophilized solid; solubility in sterile water or mild acidic buffer.

SECTION 4: QUALITY ASSURANCE

Produced under GMP-like, ISO-aligned procedures for research chemicals, with lot-specific identity confirmation by mass spectrometry and purity profiling by HPLC. Each batch undergoes peptide content verification, residual solvent screening, and bioburden assessment suitable for laboratory research. A Certificate of Analysis (CoA) is provided for every lot, detailing analytical methods, results, and specifications. Stringent documentation and traceability support reproducibility in scientific research.

SECTION 5: STORAGE & HANDLING

Store lyophilized peptide at -20°C or below in a desiccated, light-protected environment. For reconstitution, use sterile water or appropriate buffer (e.g., 0.1% acetic acid) with gentle swirling; avoid vigorous agitation. After reconstitution, aliquot to prevent repeat freeze–thaw cycles; short-term storage 2–8°C for up to 1 week, longer-term at -20°C to -80°C. Stability is maximized under inert atmosphere and low humidity. Use aseptic technique and appropriate PPE; dispose of unused research chemical according to institutional guidelines.

SECTION 6: COMPLIANCE & DISCLAIMERS

This product is intended exclusively for laboratory research use by qualified professionals. Not approved for human consumption, veterinary applications, or clinical use. Purchasers must be affiliated with a research institution or possess appropriate qualifications. All research must comply with applicable local, state, and federal regulations. The statements regarding research applications have not been evaluated by the FDA. Additional notice: not a drug, food, or cosmetic; no medical, diagnostic, or therapeutic claims are made or implied. By ordering, you acknowledge responsibility for safe handling and lawful use in scientific research.