SECTION 1: INTRODUCTION

CJC-1295 (NO DAC) 10 mg – Lab Research Supply is a synthetic peptide analog of growth hormone–releasing hormone (GHRH), commonly referred to in the literature as Mod GRF(1–29). As a growth hormone secretagogue used strictly as a research peptide, this laboratory grade material is valuable for probing somatotropic axis regulation, neuroendocrine signaling, and peptide stability mechanisms. Its short-acting, non-DAC format enables precise experimental control in in-vitro studies and preclinical peptide research.

SECTION 2: RESEARCH APPLICATIONS

• Investigated in studies examining GHRH receptor engagement and downstream cAMP/PKA pathway activation in pituitary cell models.
• Research has explored its role in characterizing pulsatile growth hormone secretory dynamics and assay-based biomarker responses.
• In-vitro studies have demonstrated utility for assessing peptide half-life, proteolytic resistance, and formulation variables in high purity peptide systems.
• Animal model research suggests suitability for evaluating somatotropic axis signaling, tissue remodeling markers, and metabolic pathway readouts under controlled conditions.
• Laboratory investigations focus on neuroprotective signaling cascades, cytokine profiling in anti-inflammatory research, and recovery-related gene expression panels.
• Peptide research frequently employs CJC-1295 (NO DAC) for research to benchmark short-acting GHRH analogs against longer-acting constructs.

SECTION 3: TECHNICAL SPECIFICATIONS

Purity: ≥98% (HPLC). Form: lyophilized powder, 10 mg/vial; appearance: white to off-white, hygroscopic. Classification: synthetic GHRH(1–29) analog, tetrasubstituted to enhance enzymatic stability; C-terminus amidated. Molecular weight: approximately 3.3–3.4 kDa (sequence-dependent; see CoA). Molecular formula: sequence-specific; provided on Certificate of Analysis. CAS: variant-specific listings may not be assigned for the NO DAC format. Solubility: sterile water or mild acidic buffer (e.g., 0.1% acetic acid), as appropriate for scientific research.

SECTION 4: QUALITY ASSURANCE

Produced to stringent laboratory-grade standards with controlled peptide synthesis and purification workflows. Each batch is verified by HPLC and LC-MS; peptide content may be confirmed by amino acid analysis. Third-party testing supports identity and purity confirmation. Certificate of Analysis is provided for every lot. Batch-level documentation, retention samples, and traceability procedures support reproducibility across scientific research programs.

SECTION 5: STORAGE & HANDLING

Store lyophilized peptide at -20°C or below, protected from light and moisture. Stable for long-term storage when frozen; minimize temperature excursions. After reconstitution, store at 2–8°C for short-term use; for extended use, aliquot and freeze at -20°C to avoid repeated freeze–thaw cycles. Reconstitute with sterile solvent under aseptic conditions; filter if required by protocol. Handle as a research chemical with appropriate PPE and sterile technique. Shelf life is lot-dependent; refer to CoA.

SECTION 6: COMPLIANCE & DISCLAIMERS

This product is intended exclusively for laboratory research use by qualified professionals. Not approved for human consumption, veterinary applications, or clinical use. Purchasers must be affiliated with a research institution or possess appropriate qualifications. All research must comply with applicable local, state, and federal regulations. The statements regarding research applications have not been evaluated by the FDA. Additional notice: not for diagnostic, therapeutic, or household use. End user assumes all responsibility for safe handling and lawful utilization.