SECTION 1: INTRODUCTION

5-amino-1 MQ 5 MG – Lab Research Supply features 5-amino-1-methylquinolinium (commonly abbreviated 5-amino-1MQ), a laboratory-grade research chemical widely used in metabolic and inflammation-focused scientific research. Although often listed alongside research peptides, 5-amino-1MQ is a synthetic small-molecule NNMT inhibitor rather than a peptide, valued for probing nicotinamide and methylation pathways in preclinical systems. Its relevance spans anti-inflammatory, neuroprotective, longevity, and metabolic research contexts.

SECTION 2: RESEARCH APPLICATIONS

• Investigated in studies examining NNMT inhibition and downstream effects on nicotinamide recycling and cellular NAD+ metabolism.
• Research has explored its role in modulating adipocyte bioenergetics, methyl donor (SAM/SAH) balance, and metabolic gene expression in cell-based models.
• In-vitro studies have demonstrated concentration-dependent effects on inflammatory signaling pathways and cytokine expression profiles.
• Animal model research suggests pathway-mediated influences on energy expenditure markers and adipose tissue remodeling proxies.
• Laboratory investigations focus on neuroinflammation, oxidative stress responses, and neuronal survival markers in preclinical systems.
• Additional research evaluates fibrotic signaling and extracellular matrix turnover relevant to tissue remodeling studies.

SECTION 3: TECHNICAL SPECIFICATIONS

High purity peptide-grade research chemical, ≥98% purity by HPLC. Commonly provided as the 5-amino-1-methylquinolinium salt (frequently iodide); exact molecular formula and molecular weight may vary with counterion and are reported on the lot-specific Certificate of Analysis. Supplied as a crystalline powder, off-white to light tan in appearance, suitable for in-vitro studies and peptide research workflows. CAS and precise identifiers are salt-form dependent; sequence not applicable (non-peptidic).

SECTION 4: QUALITY ASSURANCE

Produced under controlled, laboratory-grade conditions with rigorous in-process controls. Each lot undergoes orthogonal identity and purity testing (HPLC, LC–MS; NMR as applicable), residual solvent analysis, and moisture determination. Batch traceability is maintained end-to-end, and a detailed Certificate of Analysis is available for every lot. Release specifications emphasize high purity, identity confirmation, and consistency suitable for reproducible scientific research.

SECTION 5: STORAGE & HANDLING

Store unopened material at –20°C in a desiccated, light-protected environment. When preparing stock solutions, use an appropriate solvent (e.g., DMSO or aqueous buffers as compatible), filter if required for your protocol, and aliquot to avoid repeated freeze–thaw cycles. Stable for 24 months unopened under recommended conditions; refer to the COA for lot-specific stability. Handle using standard laboratory PPE and good research practices.

SECTION 6: COMPLIANCE & DISCLAIMERS

This product is intended exclusively for laboratory research use by qualified professionals. Not approved for human consumption, veterinary applications, or clinical use. Purchasers must be affiliated with a research institution or possess appropriate qualifications. All research must comply with applicable local, state, and federal regulations. The statements regarding research applications have not been evaluated by the FDA. This research peptide-grade chemical is not a drug, diagnostic, or household item and is supplied non-sterile for in-vitro research only.