SECTION 1: INTRODUCTION

Alprostadil (Prostaglandin E1, PGE1) 20 MCG – Lab Research Supply is a laboratory grade eicosanoid signaling molecule classified as a prostaglandin E-series analog (non-peptidic). Recognized for its well-characterized activity at EP receptors and cAMP pathways, Alprostadil for research is valued as a precise pharmacologic probe in scientific research. It supports controlled in‑vitro studies in vascular biology, platelet function, and cell signaling, and is frequently used alongside peptide research workflows and other research chemicals.

SECTION 2: RESEARCH APPLICATIONS

• Investigated in studies examining EP receptor–mediated cAMP signaling and downstream PKA-dependent pathways in endothelial and smooth muscle systems.
• Research has explored its role in modulation of vascular tone, microcirculatory dynamics, and endothelial barrier function in controlled laboratory settings.
• In‑vitro studies have demonstrated concentration-dependent effects on platelet aggregation and prostanoid signaling balance.
• Animal model research suggests utility as a tool compound for probing smooth muscle relaxation and tissue perfusion mechanisms.
• Laboratory investigations focus on inflammatory mediator cross-talk, oxidative stress responses, and ischemia–reperfusion paradigms.
• Additional studies assess receptor selectivity, desensitization kinetics, and interactions with nitric oxide signaling in preclinical models.

SECTION 3: TECHNICAL SPECIFICATIONS

This high purity research chemical is supplied as a 20 mcg unit in an amber vial. Typical purity is ≥98% (HPLC); lot-specific values are reported on the Certificate of Analysis. Molecular formula: C20H34O5. Molecular weight: 354.49 g/mol. CAS: 745-65-3. Appearance: white to off‑white solid; light- and air-sensitive. Solubility: soluble in ethanol and DMSO; limited aqueous solubility. Non-peptidic structure consistent with Prostaglandin E1; no amino acid sequence.

SECTION 4: QUALITY ASSURANCE

Produced under documented laboratory-grade SOPs with rigorous batch testing. Identity and purity are verified by HPLC and LC–MS, with supporting NMR as applicable. Each batch is accompanied by a lot-specific COA detailing analytical methods, purity, and retest date. Processes follow robust quality management practices aligned with GMP principles for research materials.

SECTION 5: STORAGE & HANDLING

Store at −20°C or below, desiccated, protected from light and oxygen. Stable when stored as directed; refer to COA for retest/expiry. For reconstitution, prepare concentrated stocks in anhydrous ethanol or DMSO, then dilute into assay media immediately prior to use. Dispense into single-use aliquots to avoid repeated freeze–thaw. Use amber glassware where possible to minimize adsorption and photodegradation. Handle with standard laboratory PPE.

SECTION 6: COMPLIANCE & DISCLAIMERS

This product is intended exclusively for laboratory research use by qualified professionals. Not approved for human consumption, veterinary applications, or clinical use. Purchasers must be affiliated with a research institution or possess appropriate qualifications. All research must comply with applicable local, state, and federal regulations. The statements regarding research applications have not been evaluated by the FDA. Not sterile or pyrogen-tested; not for diagnostic procedures. Buyer assumes all responsibility for safe handling and lawful use.

Keywords: research peptide, laboratory grade, Alprostadil for research, high purity peptide, research chemical, scientific research, in‑vitro studies, peptide research, vascular biology research, platelet function research.