SECTION 1: INTRODUCTION

GDF-8 (Growth Differentiation Factor 8; commonly known as Myostatin) 1 mg – Lab Research Supply is a laboratory-grade recombinant peptide representing the mature domain of myostatin. Classified as a TGF-β family growth factor and supplied as a synthetic peptide analogue for research, this product is engineered for use in basic and translational scientific research. GDF-8 (Myostatin) for research is widely cited in studies of muscle biology and cell signaling, making it a valuable research peptide for in-vitro and preclinical investigations.

SECTION 2: RESEARCH APPLICATIONS

• Investigated in studies examining regulation of skeletal muscle differentiation and myogenesis in cell culture models
• Research has explored its role in TGF-β signaling pathways and SMAD-mediated transcriptional regulation
• In-vitro studies have demonstrated effects on myoblast proliferation, differentiation, and fusion
• Animal model research suggests utility in examining muscle atrophy, regeneration, and metabolic phenotypes (preclinical contexts only)
• Laboratory investigations focus on satellite cell biology, receptor binding assays (ActRIIB), and peptide-protein interaction studies

SECTION 3: TECHNICAL SPECIFICATIONS

High purity peptide supplied as lyophilized powder (1 mg vial). Purity: ≥98% by HPLC. Approximate molecular weight: ~12.5 kDa for the mature monomer; molecular formula and exact mass vary with sequence variant and are provided on the Certificate of Analysis. Appearance: white to off-white freeze-dried powder. Sequence information (mature domain/isoform) and peptide lot-specific data available upon request. CAS number and specific isoform identifiers are provided on batch documentation when applicable.

SECTION 4: QUALITY ASSURANCE

Manufactured under laboratory-grade, controlled conditions with documented quality control. Each batch undergoes HPLC purity analysis and mass spectrometry confirmation; Certificate of Analysis (CoA) included with shipment. Batch traceability and analytical data are maintained; third-party testing is available upon request. This product is intended and labeled for research use and is produced to support reproducible peptide research.

SECTION 5: STORAGE & HANDLING

Store lyophilized product at -20°C or colder. When stored properly, stability is maintained for 12 months unopened; minimize freeze-thaw cycles after reconstitution. Reconstitution guidelines: use sterile, nuclease-free water or appropriate buffer; avoid repeated handling and prepare aliquots for experiments. Handle per institutional safety protocols, use appropriate PPE, and consult the Safety Data Sheet (SDS) prior to use.

SECTION 6: COMPLIANCE & DISCLAIMERS

This product is intended exclusively for laboratory research use by qualified professionals. Not approved for human consumption, veterinary applications, or clinical use. Purchasers must be affiliated with a research institution or possess appropriate qualifications. All research must comply with applicable local, state, and federal regulations. The statements regarding research applications have not been evaluated by the FDA. Not for diagnostic or therapeutic use. By purchasing, the buyer acknowledges responsibility for compliance with institutional and regulatory requirements.